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Newly discovered trigger for major depression opens new possibilities for treatmentsA common amino acid, glycine, can deliver a “slow-down” signal to the brain, likely contributing to major depression, anxiety and other mood disorders in some people, scientists at the Wertheim UF Scripps Institute for Biomedical Innovation & Technology have found. The discovery, outlined Thursday in the journal Science, improves understanding of the biological causes of major depression and could accelerate efforts to develop new, faster-acting medications for such hard-to-treat mood ... University of Florida - 3/30/2023Binge eating brain circuits similar to those associated with drug use, other habit-forming behaviors: Study could lead to new ways to treat eating disordersScientists have uncovered the brain circuits that may underlie binge eating disorder and related conditions. The neural wiring is the same as that tied to psychiatric conditions such as drug addiction and obsessive-compulsive disorder. The work could lead to new ways to understand and treat eating disorders, says Rebecca Boswell, a clinical psychologist at Princeton University who was not involved with the study. Indeed, she says, some of the same drugs and strategies that seek to reverse ... American Association for the Advancement of Science - 3/29/2023The more traumatic the childhood, the angrier the adult: Childhood trauma linked with greater tendency to anger in anxious or depressed patientsScientists have found that depression and anxiety sufferers who have had a traumatic childhood tend to grow up as angry adults, and the worse the trauma, the angrier the adult. This can affect personal mental health and social interaction, but also makes it more difficult to treat the depression and anxiety. This work is presented at the European Congress of Psychiatry in Paris. Previously, the researchers had found that more than 40% of patients with both anxiety and depression had ... European Psychiatric Association - 3/25/2023Use of melatonin linked to decreased self-harm in young peopleMedical sleep treatment may reduce self-harm in young people with anxiety and depression, an observational study from Karolinska Institutet in Sweden suggests. The risk of self-harm increased in the months preceding melatonin prescription and decreased thereafter, especially in girls. The study is published in The Journal of Child Psychology and Psychiatry. Melatonin is a hormone that controls the sleep-wake cycle and is the most commonly prescribed drug for sleep disturbances in ... Karolinska Institutet - 3/23/2023Depressed, and aging fast: Older adults with late-in-life-depression age biologically older than their chronological peersOlder adults with depression are actually aging faster than their peers, UConn Center on Aging researchers report. “These patients show evidence of accelerated biological aging, and poor physical and brain health,” which are the main drivers of this association, says Breno Diniz, a UConn School of Medicine geriatric psychiatrist and author of the study, which appears in Nature Mental Health on March 22. Diniz and colleagues from several other institutions looked at 426 people with ... University of Connecticut - 3/22/2023Researchers find strong adolescent-parent relationships lead to better long-term health outcomes in young adultsResearchers from Children's Hospital of Philadelphia (CHOP) have found that adolescents who report strong relationships with their parents have better long-term health outcomes. Study findings, published today in JAMA Network Open, suggest that investments in improving parent-adolescent relationships could help improve general health, mental health and sexual, health while also reducing substance use in young adulthood. Prior research shows that positive characteristics of ... Children's Hospital of Philadelphia - 3/21/2023New evidence: Immune system cells in the gut linked to stress-induced depressionIn experiments with mice and humans, a team led by Johns Hopkins Medicine researchers says it has identified a particular intestinal immune cell that impacts the gut microbiome, which in turn may affect brain functions linked to stress-induced disorders such as depression. Targeting changes mediated by these immune cells in the gut, with drugs or other therapies, could potentially bring about new ways to treat depression. Johns Hopkins Medicine - 3/20/2023Attending live sport improves wellbeing – study: Research is first to demonstrate major benefits across large adult populationNew scientific research has found that attending live sporting events improves levels of wellbeing and reduces feelings of loneliness. Published in the journal Frontiers in Public Health, the research is the first large-scale study to examine the benefits of attending any type of live sporting event. The study, carried out by academics from Anglia Ruskin University’s School of Psychology and Sport Science, used data from 7,209 adults, aged 16-85, living in England who participated in the ... Anglia Ruskin University - 3/17/2023Progress in unlocking the brain's "code" for depressionClinical depression is a common psychiatric condition with often devastating consequences. A new study in Biological Psychiatry, published by Elsevier, advances our fundamental understanding of the neural circuitry of depression in the human brain. Treatment of depression is complicated by the disease’s high heterogeneity and notable complexity. Medication to treat depression is available, but one third of patients do not respond to these first-line drug treatments. Other treatments ... Elsevier - 3/16/2023How moms and dads view each other as co-parents affects kids: Poor outcomes when dads unhappy with co-parenting relationshipHow mothers and fathers see each other as co-parents of their children plays a key role in how well-adjusted their kids become, a new study suggests. Researchers found that, in a sample of low-income couples, children have the best outcomes when both parents saw their co-parenting relationship as highly positive and worst when both parents viewed their relationship as poor. However, child outcomes diverged when couples saw their co-parenting relationship as moderately good, ... Ohio State University - 3/15/2023On pandemic’s third anniversary, loneliness and isolation are down, but still high, among older adultsAfter three years of pandemic living, loneliness, isolation and lack of social contact have finally started to decline among older adults, a new poll shows. But one in three people between the ages of 50 and 80 still say they sometimes or often experienced these feelings, or sometimes go a week or longer without social contact with someone from outside their home. That’s down from about half of older adults in June 2020. The percentages who currently feel lonely, isolated or lacking ... Michigan Medicine - University of Michigan - 3/13/2023'All work, no independent play' cause of children's declining mental healthAnxiety and depression among school-aged children and teens in the United States are at an all-time high. Sadly, in 2021, child and adolescent mental health was declared a national emergency. Although a variety of causes are thought to contribute to this decline in mental health, a new study by three prominent researchers specializing in child development points to independent "child's play." Findings, published in the Journal of Pediatrics, suggest that the rise in mental health disorders ... Florida Atlantic University - 3/9/2023MIND and Mediterranean diets associated with fewer Alzheimer's plaques and tanglesPeople who eat diets rich in green leafy vegetables as well as other vegetables, fruits, whole grains, olive oil, beans, nuts and fish may have fewer amyloid plaques and tau tangles in their brain -- signs of Alzheimer's disease -- than people who do not consume such diets, according to a study published in the March 8, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study examined how closely people followed the MIND and Mediterranean ... American Academy of Neurology - 3/8/2023Are you chasing your dreams or running from your fears? A new study, the first of its kind, has shown that when it comes to pursuing personal goals and protecting your mental wellbeing it pays to understand your underlying motivesA new Edith Cowan University (ECU) study, the first of its kind, has shown that when it comes to pursuing personal goals and protecting your mental wellbeing it pays to understand your underlying motives. ECU researchers Bridget Robson and Professor Joanne Dickson surveyed 210 participants to investigate the relationship between underlying goal motives, emotion regulation, and anxiety and depression. The research examined two types of motives that underpin personal goal pursuit ... Edith Cowan University - 3/6/2023COVID-19 pandemic increased rates and severity of depression, whether people were infected or notThe COVID-19 pandemic impacted just about every part of people’s lives. Quarantining, social distancing, societal disruptions and an ever-shifting, uncertain landscape of rules and restrictions and variants created stress and isolation that impacted the mental health of millions of Americans. Now, in a new study of nearly 136,000 patients from Intermountain Health in Salt Lake City, researchers found that depressive symptoms and severity of depression was significant among ... Intermountain Healthcare - 3/4/2023Pregnant patients with anxiety have altered immune systemsThe immune system of pregnant women with anxiety is biologically different from that of pregnant women without anxiety, according to new research from Weill Cornell Medicine, Johns Hopkins University School of Medicine and Columbia University Irving Medical Center investigators. The study, published Sept. 14 in Brain, Behavior and Immunity, demonstrates that pregnant women with anxiety have higher levels of certain immune cells known as cytotoxic T cells; these cells attack ... Weill Cornell Medicine - 3/2/2023Social workers experienced depression, PTSD, and anxiety at alarming rates during pandemicA new study published in the journal International Social Work has uncovered concerning rates of depression, post-traumatic stress disorder (PTSD) and anxiety among social workers. Stressors related to COVID-19 were the strongest factors associated with the negative mental health outcomes. Those who experienced a higher number of pandemic-related stressors — such as health concerns, increased caregiving responsibilities, violence in the home, family stress due to confinement, ... University of Toronto - 3/1/2023Regular physical activity can improve adolescents’ mental health and help with behavioural difficulties, research suggestsRegular physical activity can improve adolescents' mental health and help with behavioural difficulties, research suggests. Engaging in regular moderate to vigorous physical activity at age 11 was associated with better mental health between the ages of 11 and 13, the study found. Physical activity was also associated with reduced hyperactivity and behavioural problems, such as loss of temper, fighting with other children, lying, and stealing, in young people. University of Edinburgh - 3/1/2023Lending a paw for defense veterans: 'Clear evidence' that assistance dogs help improve mental healthA new Australian study focused on defence veterans' mental health has found strong evidence that assistance dogs used in conjunction with traditional therapies provide the most effective treatment outcomes. Almost 90 per cent of veterans reported improvements in their post-traumatic stress, depression and anxiety 12 months after being matched to an assistance dog, according to researchers from the University of South Australia (UniSA), University of Adelaide, and Military and ... University of South Australia - 3/1/2023Being flexible is key to protecting mental wellbeing in people with chronic painChronic pain impacts around 20 per cent of the population. Along with the medical and physical effects it can have far-reaching consequences for employment, lifestyle and mental health. A new Edith Cowan University (ECU) study has found that for people living with chronic pain it's not necessarily how intense their pain is, but the extent to which it interferes with their daily life that can pose the biggest threat to their mental health. ECU researchers Tara Swindells and Professor ... Edith Cowan University - 2/27/2023Excessive screen time linked to suicidal behaviors in US preteens: Watching videos, playing video games, texting, and video chatting tied to suicidal behaviorsAmidst the worsening teen mental health crisis and new legislation proposing to ban children under 16 from using social media, a new study finds that greater screen time among children 9-11 is associated with a higher risk of developing suicidal behaviors two years later. The study, published in Preventive Medicine, finds that each additional hour of screen time is associated with a 9% higher risk of reporting suicidal behavior two years later. In particular, each extra hour spent watching ... University of Toronto - 2/27/2023Time in nature may help older adults with improved health, purpose in lifeOver time, research has demonstrated that spending time in nature confers psychological, emotional and physical benefits. To maximize benefits of spending time in nature for people over the age of 65, researchers from Penn State; National Open University, Taiwan; and Lunghwa University of Science and Technology, Taiwan, studied the attitudes, beliefs and actions of a group of elders -- people over the age of 65 -- who regularly spent time in a natural area. The researchers found ... Penn State - 2/24/2023Exercise more effective than medicines to manage mental healthUniversity of South Australia researchers are calling for exercise to be a mainstay approach for managing depression as a new study shows that physical activity is 1.5 times more effective than counselling or the leading medications. Published in the British Journal of Sports Medicine, the review is the most comprehensive to date, encompassing 97 reviews, 1039 trials and 128,119 participants. It shows that physical activity is extremely beneficial for improving symptoms of depression, ... University of South Australia - 2/23/2023Irritable bowel syndrome (IBS) patients suffer significantly higher rates of anxiety, depression, and suicidal ideation than those without IBSNew research from the University of Missouri School of Medicine has established a link between irritable bowel syndrome (IBS) and mental health challenges, such as anxiety, depression, and suicidal ideation. The research highlights the need for health professionals to evaluate and treat associated psychiatric co-morbidities in IBS patients to improve their overall health and quality of life. IBS is a chronic disorder of the stomach and intestines affecting up to 15 percent of the population. University of Missouri-Columbia - 2/22/2023Can the lingering effects of a mild case of COVID-19 change your brain? Study finds brain changes in people with anxiety, depression symptomsPeople with long COVID who experience anxiety and depression months after a mild case of COVID-19 may have brain changes that affect the function and structure of the brain, according to a preliminary study released today, February 20, 2023, that will be presented at the American Academy of Neurology’s 75th Annual Meeting being held in person in Boston and live online from April 22-27, 2023. “There is still much to learn about long COVID, which includes a wide range of health ... American Academy of Neurology - 2/20/2023Psychological stress impedes performance, even for Olympic athletesThe 2020 Tokyo Olympics were unique not just for taking place during the COVID-19 pandemic but for being the first athletic event to measure and broadcast competitors' heart rates as world-class archers took a shot at Olympic gold. Analysis of these biometric data by Yunfeng Lu (Nanjing University) and Songfa Zhong (National University of Singapore, New York University Abu Dhabi) in Psychological Science provides empirical support for something sports fans have long suspected: When ... Association for Psychological Science - 2/16/2023The relationship between ghosting and closure: Study shows need for closure can magnify emotional effect of ghostingOdds are, you know someone who has been ghosted. And according to a new study from the University of Georgia, it can be a haunting experience. A recent study conducted by researcher and corresponding author Christina Leckfor and University of Mississippi researcher Natasha Wood found nearly two-thirds of participants have ghosted -- ended a relationship by ignoring the other person, without offering a clear explanation -- and have been ghosted. And as online dating, ... University of Georgia - 2/13/2023A sense of purpose may have significant impact on teens' emotional well-beingAdolescents who feel a greater sense of purpose may be happier and more satisfied with life than peers who feel less purposeful, suggests a recent study of more than 200 teens. Studies with adults have suggested that a sense of purpose in life is an integral component of well-being that fuels hope and optimism and has a variety of positive effects on individuals' physical and mental health. However, less is known about the effects of purposefulness in adolescents, who, while ... University of Illinois at Urbana-Champaign, News Bureau - 2/13/2023Warning signs of poor mental health in athletes: ‘Put down’ language is a key indicator of poor mental health in athletes, recent research showsMore than 400 athletes across a variety of sports, ages and levels of experience were questioned for the study by sports psychology experts from Staffordshire University and Manchester Metropolitan University. The findings reveal that athletes' belief systems -- specifically irrational beliefs -- are related to poorer self-confidence, and in turn, greater competitive anxiety and depressive symptoms. Phrases that reflect self-depreciating beliefs such as "if I lose, I'm a failure" or "If I ... Staffordshire University - 2/8/2023Video game playing causes no harm to young children's cognitive abilities, study findsParents: It might be time to rethink your family’s video-gaming rules. New research findings challenge the fears parents have been hearing for years that children who spend hour after hour playing video games, or choose games of certain genres, would manifest unhealthy results in their cognitive ability. “Our studies turned up no such links, regardless of how long the children played and what types of games they chose,” said Jie Zhang, associate professor of curriculum and instruction at ... University of Houston - 2/7/2023Brain structural differences observed in children with conduct disorder with and without childhood maltreatmentCharacterized by antisocial behaviors and low academic achievement, conduct disorder (CD) impacts an estimated 9.5% of individuals in the United States. Childhood maltreatment is a major risk factor for CD. Past CD studies have identified structural alterations in various brain regions, such as those implicated in emotion processing, learning, and social cognition. A new study appearing in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, published by Elsevier, has ... Elsevier - 2/7/2023Just one quality conversation with a friend boosts daily well-being: In-person beats online, but a phone call will doConversing with a friend just once during the day to catch up, joke around or tell them you're thinking of them can increase your happiness and lower your stress level by day's end. These are among the results of a new study co-authored by University of Kansas professor of Communication Studies and friendship expert Jeffrey Hall. "Quality Conversation Can Increase Daily Well-Being" was published in the journal Communication Research by Hall and co-authors Amanda Holmstrom, ... University of Kansas - 2/2/2023Study finds new association between social isolation and dementia risk factorsSocial lifestyle determinants, including social isolation, are associated with neurodegeneration risk factors, according to a new study published this week in the open-access journal PLOS ONE by Kimia Shafighi of McGill University, Canada, and colleagues. Alzheimer's disease and related dementias (ADRD) is a growing public health crisis, with an annual global cost of more than $1 trillion US. There has been increasing evidence that social isolation is associated with an increased risk of ... PLOS - 2/1/2023Shining a light on the biological origins of PTSD: A Tufts-led team finds a brain marker that indicates vulnerability to developing post-traumatic stress disorderUnderstanding one’s susceptibility to developing post-traumatic stress disorder (PTSD) is important. If you knew you were at risk, for example, you might steer clear of jobs that carry more likelihood of high stress and potential trauma or seek treatment as soon as you experienced a potentially triggering event. Now a research team has found a marker that indicates vulnerability to the disorder. They discovered that heightened activation in one particular brain region in response to ... Tufts University - 2/1/2023Moderate and intense physical activity favors good sleep: New study conducted in Japan emphasizes the importance of physical activity in improving sleep quality in middle-aged Japanese womenProper sleep is critical for the maintenance of good health, and vice versa -- a healthy lifestyle has been found to improve sleep quality. To better examine the relationship between physical activity and sleep, a team of researchers conducted a comprehensive study among middle-aged Japanese people. By outlining the factors improving sleep quality, this line of research can hopefully help in preventing sleep-related disorders. An adequate amount of good-quality sleep is essential for the ... Japan Advanced Institute of Science and Technology - 1/31/2023Poor coparenting linked to depression in dadsDads are more likely to feel depressed when their kids are toddlers if their coparenting relationships are poor in the months after birth, a new study by researchers at Karolinska Institutet in Sweden shows. The findings are published in the Journal of Affective Disorders. “We have a lot to gain as a society if we support coparenting relationships more during the early stages of parenthood,” says Michael Wells, associate professor at the Department of Women’s and Children’s Health, ... Karolinska Institutet - 1/24/2023When chronic stress activates these neurons, behavioral problems like loss of pleasure, depression resultIt's clear that chronic stress can impact our behavior, leading to problems like depression, reduced interest in things that previously brought us pleasure, even PTSD. Now scientists have evidence that a group of neurons in a bow-shaped portion of the brain become hyperactive after chronic exposure to stress. When these POMC neurons become super active, these sort of behavioral problems result and when scientists reduce their activity, it reduces the behaviors, they report in the ... Medical College of Georgia at Augusta University - 1/24/2023Scientists explain emotional 'blunting' caused by common antidepressantsScientists have worked out why common anti-depressants cause around a half of users to feel emotionally 'blunted'. In a study published today, they show that the drugs affect reinforcement learning, an important behavioural process that allows us to learn from our environment. According to the NHS, more than 8.3 million patients in England received an antidepressant drug in 2021/22. A widely-used class of antidepressants, particularly for persistent or severe cases, is selective ... University of Cambridge - 1/22/2023Older adults with asthma at high risk for depression during the COVID-19 pandemicA recent, prospective study of approximately 2,000 older adults in Canada published online this month in the journal Respiratory Medicine found that older adults with asthma were at high risk of depression during the COVID-19 pandemic. For older adults with asthma who had experienced depression in the past, the numbers were extremely worrying, with approximately one-half experiencing a recurrence of depression during the autumn of 2020, which was significantly higher than ... University of Toronto - 1/19/2023
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